Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002740.6

p.T239A

c.715A>G

Surrounding Variants

1 paper

NM_002740.6

p.R240T

c.719G>C

1 paper

NM_002740.6

p.A236S

c.706G>T

1 paper

NM_002740.6

p.S242T

c.725G>C

2 papers

NM_002740.6

p.G243D

c.728G>A

1 paper

NM_002740.6

p.K244_A245insCC

c.730_734ins6

1 paper

NM_002740.6

p.A245_S246insCC

c.733_737ins6

1 paper

NM_002740.6

p.S247F

c.740C>T

1 paper

NM_002740.6

p.G250S

c.748G>A

1 paper

NM_002740.6

p.D253N

c.757G>A

1 paper

NM_002740.6

p.R258W

c.772C>T

1 paper

NM_002740.6

p.R258R

c.774G>C

2 papers

NM_002740.6

p.G263R

c.787G>A