Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002740.6

p.G398S

c.1192G>A

Surrounding Variants

4 papers

NM_002740.6

p.D396E

c.1188C>A

4 papers

NM_002740.6

p.D396E

c.1188C>G

1 paper

NM_002740.6

p.T395I

c.1184C>T

1 paper

NM_002740.6

p.L394F

c.1180C>T

1 paper

NM_002740.6

p.D387Y

c.1159G>T

2 papers

NM_002740.6

p.L385F

c.1155A>C

2 papers

NM_002740.6

p.L385F

c.1155A>T

1 paper

NM_002740.6

p.L385S

c.1154T>C

1 paper

NM_002740.6

p.N383K

c.1149T>A

1 paper

NM_002740.6

p.N383K

c.1149T>G

2 papers

NM_002740.6

p.N383S

c.1148A>G

1 paper

NM_002740.6

p.N383I

c.1148A>T