Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002740.6

p.V473Splc

c.1418-141G>A

Surrounding Variants

1 paper

NM_002740.6

p.R480S

c.1438C>A

14 papers

NM_002740.6

p.R480C

c.1438C>T

2 papers

NM_002740.6

p.R480H

c.1439G>A

1 paper

NM_002740.6

p.I481T

c.1442T>C

1 paper

NM_002740.6

p.P482Q

c.1445C>A

1 paper

NM_002740.6

p.L485M

c.1453C>A

1 paper

NM_002740.6

p.K499_D500Splc

c.1498-3T>C

1 paper

NM_002740.6

p.K499_D500Splc

c.1498-1G>T

1 paper

NM_002740.6

p.E503K

c.1507G>A

1 paper

NM_002740.6

p.E503G

c.1508A>G

2 papers

NM_002740.6

p.R504Q

c.1511G>A

1 paper

NM_002740.6

p.G512E

c.1535G>A