Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002740.6

p.G545G

c.1635G>T

Surrounding Variants

1 paper

NM_002740.6

p.L549F

c.1647G>C

1 paper

NM_002740.6

p.L549F

c.1647G>T

2 papers

NM_002740.6

p.F539L

c.1617T>A

2 papers

NM_002740.6

p.F539L

c.1617T>G

2 papers

NM_002740.6

p.F539L

c.1615T>C

2 papers

NM_002740.6

p.P538S

c.1612C>T

1 paper

NM_002740.6

p.V535L

c.1603G>C

1 paper

NM_002740.6

p.V535L

c.1603G>T

1 paper

NM_002740.6

p.E559K

c.1675G>A

1 paper

NM_002740.6

p.E559*

c.1675G>T

1 paper

NM_002740.6

p.P560R

c.1679C>G

2 papers

NM_002740.6

p.Q562*

c.1684C>T