Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.K604E

c.1810A>G

Surrounding Variants

1 paper

NM_006257.5

p.K604R

c.1811A>G

1 paper

NM_006257.5

p.R600L

c.1799G>T

2 papers

NM_006257.5

p.R600W

c.1798C>T

1 paper

NM_006257.5

p.F597L

c.1791T>G

1 paper

NM_006257.5

p.L610P

c.1829T>C

1 paper

NM_006257.5

p.F597L

c.1791T>A

1 paper

NM_006257.5

p.F597L

c.1789T>C

1 paper

NM_006257.5

p.K612R

c.1835A>G

1 paper

NM_006257.5

p.K612N

c.1836G>T

1 paper

NM_006257.5

p.K612N

c.1836G>C

1 paper

NM_006257.5

p.D594G

c.1781A>G

3 papers

NM_006257.5

p.D594N

c.1780G>A