Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.S577L

c.1730C>T

Surrounding Variants

1 paper

NM_006257.5

p.P578S

c.1732C>T

1 paper

NM_006257.5

p.G575C

c.1723G>T

1 paper

NM_006257.5

p.H580L

c.1739A>T

1 paper

NM_006257.5

p.G581R

c.1741G>C

1 paper

NM_006257.5

p.G581R

c.1741G>A

1 paper

NM_006257.5

p.L573M

c.1717C>A

1 paper

NM_006257.5

p.M572T

c.1715T>C

1 paper

NM_006257.5

p.D583Y

c.1747G>T

1 paper

NM_006257.5

p.D583N

c.1747G>A

1 paper

NM_006257.5

p.E571G

c.1712A>G

1 paper

NM_006257.5

p.E571K

c.1711G>A

1 paper

NM_006257.5

p.E584K

c.1750G>A