Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.D561N

c.1681G>A

Surrounding Variants

1 paper

NM_006257.5

p.S564F

c.1691C>T

1 paper

NM_006257.5

p.N557K

c.1671C>G

1 paper

NM_006257.5

p.N557K

c.1671C>A

1 paper

NM_006257.5

p.G566R

c.1696G>C

1 paper

NM_006257.5

p.G566R

c.1696G>A

1 paper

NM_006257.5

p.G566E

c.1697G>A

1 paper

NM_006257.5

p.L569F

c.1705C>T

1 paper

NM_006257.5

p.L551F

c.1653G>T

1 paper

NM_006257.5

p.L551F

c.1653G>C

1 paper

NM_006257.5

p.E571K

c.1711G>A

1 paper

NM_006257.5

p.E571G

c.1712A>G

1 paper

NM_006257.5

p.I550N

c.1649T>A