Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.P334L

c.1001C>T

Surrounding Variants

1 paper

NM_006257.5

p.L333S

c.998T>C

1 paper

NM_006257.5

p.T335K

c.1004C>A

1 paper

NM_006257.5

p.P336L

c.1007C>T

1 paper

NM_006257.5

p.P336delins

c.1006_1007delinsTT

1 paper

NM_006257.5

p.P336P

c.1008G>A

1 paper

NM_006257.5

p.G337R

c.1009G>C

1 paper

NM_006257.5

p.G337R

c.1009G>A

1 paper

NM_006257.5

p.G337E

c.1010G>A

3 papers

NM_006257.5

p.P330L

c.989C>T

1 paper

NM_006257.5

p.I324_A328del0

c.971_982del12

1 paper

NM_006257.5

p.E327K

c.979G>A

1 paper

NM_006257.5

p.N326I

c.977A>T