Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.R312K

c.935G>A

Surrounding Variants

1 paper

NM_006257.5

p.R312I

c.935G>T

1 paper

NM_006257.5

p.F311C

c.932T>G

1 paper

NM_006257.5

p.G314C

c.940G>T

1 paper

NM_006257.5

p.P315L

c.944C>T

1 paper

NM_006257.5

p.E308K

c.922G>A

1 paper

NM_006257.5

p.E317K

c.949G>A

1 paper

NM_006257.5

p.I318V

c.952A>G

1 paper

NM_006257.5

p.I318N

c.953T>A

1 paper

NM_006257.5

p.D306H

c.916G>C

1 paper

NM_006257.5

p.D306N

c.916G>A

1 paper

NM_006257.5

p.R305T

c.914G>C

1 paper

NM_006257.5

p.G319D

c.956G>A