Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.E308K

c.922G>A

Surrounding Variants

1 paper

NM_006257.5

p.D306H

c.916G>C

1 paper

NM_006257.5

p.D306N

c.916G>A

1 paper

NM_006257.5

p.R305T

c.914G>C

1 paper

NM_006257.5

p.R305G

c.913A>G

1 paper

NM_006257.5

p.F311C

c.932T>G

2 papers

NM_006257.5

p.L304S

c.911T>C

1 paper

NM_006257.5

p.R312I

c.935G>T

1 paper

NM_006257.5

p.R312K

c.935G>A

1 paper

NM_006257.5

p.C303F

c.908G>T

1 paper

NM_006257.5

p.C303Y

c.908G>A

1 paper

NM_006257.5

p.R302L

c.905G>T

1 paper

NM_006257.5

p.R302H

c.905G>A