Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.T165S

c.494C>G

Surrounding Variants

1 paper

NM_006257.5

p.T165S

c.493A>T

1 paper

NM_006257.5

p.F166L

c.496T>C

1 paper

NM_006257.5

p.F166L

c.498C>G

1 paper

NM_006257.5

p.F166L

c.498C>A

1 paper

NM_006257.5

p.F167L

c.499T>C

2 papers

NM_006257.5

p.F167Y

c.500T>A

1 paper

NM_006257.5

p.F167L

c.501C>G

1 paper

NM_006257.5

p.F167L

c.501C>A

1 paper

NM_006257.5

p.P168S

c.502C>T

1 paper

NM_006257.5

p.P168Q

c.503C>A

1 paper

NM_006257.5

p.Q169H

c.507G>T

1 paper

NM_006257.5

p.Q169H

c.507G>C