Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.V154I

c.460G>A

Surrounding Variants

1 paper

NM_006257.5

p.V154D

c.461T>A

1 paper

NM_006257.5

p.H155Y

c.463C>T

1 paper

NM_006257.5

p.H156Q

c.468C>G

1 paper

NM_006257.5

p.H156Q

c.468C>A

1 paper

NM_006257.5

p.K150R

c.449A>G

1 paper

NM_006257.5

p.C159S

c.475T>A

1 paper

NM_006257.5

p.C159S

c.476G>C

1 paper

NM_006257.5

p.E161Q

c.481G>C

2 papers

NM_006257.5

p.E161K

c.481G>A

1 paper

NM_006257.5

p.R146W

c.436C>T

4 papers

NM_006257.5

p.R145H

c.434G>A

2 papers

NM_006257.5

p.R145C

c.433C>T