Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006257.5

p.T136M

c.407C>T

Surrounding Variants

1 paper

NM_006257.5

p.E135Q

c.403G>C

1 paper

NM_006257.5

p.G138C

c.412G>T

1 paper

NM_006257.5

p.G138V

c.413G>T

1 paper

NM_006257.5

p.G138D

c.413G>A

1 paper

NM_006257.5

p.F139L

c.415T>C

1 paper

NM_006257.5

p.E133K

c.397G>A

1 paper

NM_006257.5

p.F139L

c.417C>G

1 paper

NM_006257.5

p.F139L

c.417C>A

1 paper

NM_006257.5

p.M131I

c.393G>T

1 paper

NM_006257.5

p.M131I

c.393G>C

1 paper

NM_006257.5

p.M131I

c.393G>A

1 paper

NM_006257.5

p.T128I

c.383C>T