Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.I72F

c.214A>T

Surrounding Variants

1 paper

NM_006257.5

p.Q71E

c.211C>G

1 paper

NM_006257.5

p.I73F

c.217A>T

2 papers

NM_006257.5

p.V74L

c.220G>T

2 papers

NM_006257.5

p.V74L

c.220G>C

1 paper

NM_006257.5

p.G67E

c.200G>A

1 paper

NM_006257.5

p.K77E

c.229A>G

1 paper

NM_006257.5

p.K77I

c.230A>T

1 paper

NM_006257.5

p.V79L

c.235G>T

1 paper

NM_006257.5

p.V79L

c.235G>C

2 papers

NM_006257.5

p.V79M

c.235G>A

1 paper

NM_006257.5

p.H63Y

c.187C>T

1 paper

NM_006257.5

p.H63N

c.187C>A