Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.Q43R

c.128A>G

Surrounding Variants

1 paper

NM_006257.5

p.G42E

c.125G>A

1 paper

NM_006257.5

p.G42R

c.124G>C

1 paper

NM_006257.5

p.G42R

c.124G>A

1 paper

NM_006257.5

p.N41S

c.122A>G

1 paper

NM_006257.5

p.N41Y

c.121A>T

1 paper

NM_006257.5

p.I46F

c.136A>T

1 paper

NM_006257.5

p.I46N

c.137T>A

1 paper

NM_006257.5

p.I46M

c.138C>G

1 paper

NM_006257.5

p.P54T

c.160C>A

1 paper

NM_006257.5

p.W56R

c.166T>C

1 paper

NM_006257.5

p.W56R

c.166T>A

1 paper

NM_006257.5

p.D61H

c.181G>C