Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.V31G

c.92T>G

Surrounding Variants

2 papers

NM_006257.5

p.V33I

c.97G>A

1 paper

NM_006257.5

p.V33G

c.98T>G

1 paper

NM_006257.5

p.C29Y

c.86G>A

1 paper

NM_006257.5

p.Y28S

c.83A>C

2 papers

NM_006257.5

p.P27L

c.80C>T

1 paper

NM_006257.5

p.P27delins

c.79_80delinsTT

1 paper

NM_006257.5

p.E35D

c.105G>T

1 paper

NM_006257.5

p.E35D

c.105G>C

1 paper

NM_006257.5

p.Y36C

c.107A>G

1 paper

NM_006257.5

p.V25L

c.73G>C

1 paper

NM_006257.5

p.E38K

c.112G>A

2 papers

NM_006257.5

p.E23K

c.67G>A