Varaico: Literature-Extracted Genetic Variants

PRKCQ

126 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

PKC_C2aa 4–113UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 160–212UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

protein kinase C theta

HGNC Previous Name

protein kinase C, theta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006257.5

p.Q21*

c.61C>T

Surrounding Variants

1 paper

NM_006257.5

p.Q21H

c.63G>T

1 paper

NM_006257.5

p.Q21H

c.63G>C

1 paper

NM_006257.5

p.G22S

c.64G>A

2 papers

NM_006257.5

p.E23K

c.67G>A

1 paper

NM_006257.5

p.C17S

c.50G>C

1 paper

NM_006257.5

p.C17S

c.49T>A

1 paper

NM_006257.5

p.V25L

c.73G>C

1 paper

NM_006257.5

p.S16F

c.47C>T

1 paper

NM_006257.5

p.S16A

c.46T>G

1 paper

NM_006257.5

p.G15R

c.43G>C

1 paper

NM_006257.5

p.G15R

c.43G>A

2 papers

NM_006257.5

p.P27L

c.80C>T