Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 106 variants

3 papers

NM_002744.6

p.S148R

c.442A>C

3 papers

NM_002744.6

p.S148R

c.444C>A

3 papers

NM_002744.6

p.S148R

c.444C>G

2 papers

NM_002744.6

p.V44M

c.130G>A

2 papers

NM_002744.6

p.R49C

c.145C>T

2 papers

NM_002744.6

p.T99P

c.295A>C

2 papers

NM_002744.6

p.E101D

c.303G>C

2 papers

NM_002744.6

p.R117Q

c.350G>A

2 papers

NM_002744.6

p.G425R

c.1273G>A

2 papers

NM_002744.6

p.G425R

c.1273G>C

2 papers

NM_002744.6

p.S514F

c.1541C>T

1 paper

NM_002744.6

p.M1V

c.1A>G