Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002744.6

p.S12C

c.34A>T

Surrounding Variants

1 paper

NM_002744.6

p.G11E

c.32G>A

1 paper

NM_002744.6

p.G13D

c.38G>A

1 paper

NM_002744.6

p.K8R

c.23A>G

1 paper

NM_002744.6

p.V16V

c.48C>A

1 paper

NM_002744.6

p.M1V

c.1A>G

1 paper

NM_002744.6

p.T29N

c.86C>A

1 paper

NM_002744.6

p.S30N

c.89G>A

1 paper

NM_002744.6

p.A33A

c.99C>T

1 paper

NM_002744.6

p.A34T

c.100G>A

1 paper

NM_002744.6

p.E38V

c.113A>T

2 papers

NM_002744.6

p.V44M

c.130G>A

1 paper

NM_002744.6

p.R45R

c.135A>G