Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002744.6

p.D88D

c.264T>C

Surrounding Variants

1 paper

NM_002744.6

p.C86C

c.258C>T

1 paper

NM_002744.6

p.C86S

c.257G>C

1 paper

NM_002744.6

p.C86S

c.256T>A

1 paper

NM_002744.6

p.L82R

c.245T>G

1 paper

NM_002744.6

p.Q52L

c.155A>T

1 paper

NM_002744.6

p.R49H

c.146G>A

2 papers

NM_002744.6

p.R49C

c.145C>T

1 paper

NM_002744.6

p.M47fs

c.139_140fs

1 paper

NM_002744.6

p.M47delFs

c.139_140delAT

1 paper

NM_002744.6

p.R45R

c.135A>G

2 papers

NM_002744.6

p.V44M

c.130G>A

1 paper

NM_002744.6

p.E38V

c.113A>T