Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002744.6

p.R121K

c.362G>A

Surrounding Variants

1 paper

NM_002744.6

p.W122*

c.365G>A

1 paper

NM_002744.6

p.W122*

c.366G>A

1 paper

NM_002744.6

p.G118E

c.353G>A

2 papers

NM_002744.6

p.R117Q

c.350G>A

1 paper

NM_002744.6

p.Y126D

c.376T>G

1 paper

NM_002744.6

p.R116P

c.347G>C

1 paper

NM_002744.6

p.R127H

c.380G>A

1 paper

NM_002744.6

p.A135T

c.403G>A

1 paper

NM_002744.6

p.R137H

c.410G>A

1 paper

NM_002744.6

p.N139_R140del2

c.415_419del6

3 papers

NM_002744.6

p.S148R

c.442A>C

1 paper

NM_002744.6

p.S148G

c.442A>G