Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002744.6

p.H169R

c.506A>G

Surrounding Variants

1 paper

NM_002744.6

p.R171H

c.512G>A

1 paper

NM_002744.6

p.L166M

c.496C>A

1 paper

NM_002744.6

p.L175L

c.525C>G

1 paper

NM_002744.6

p.C161F

c.482G>T

1 paper

NM_002744.6

p.R181W

c.541A>T

1 paper

NM_002744.6

p.A155T

c.463G>A

1 paper

NM_002744.6

p.A155P

c.463G>C

3 papers

NM_002744.6

p.S148R

c.444C>A

3 papers

NM_002744.6

p.S148R

c.444C>G

3 papers

NM_002744.6

p.S148R

c.442A>C

1 paper

NM_002744.6

p.S148G

c.442A>G

1 paper

NM_002744.6

p.S186A

c.556T>G