Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002744.6

p.R424W

c.1270C>T

Surrounding Variants

1 paper

NM_002744.6

p.L423L

c.1269G>A

2 papers

NM_002744.6

p.G425R

c.1273G>A

2 papers

NM_002744.6

p.G425R

c.1273G>C

1 paper

NM_002744.6

p.E426K

c.1276G>A

1 paper

NM_002744.6

p.E421K

c.1261G>A

1 paper

NM_002744.6

p.G429Splc

c.1285+55G>C

1 paper

NM_002744.6

p.G396S

c.1186G>A

1 paper

NM_002744.6

p.D394Y

c.1180G>T

1 paper

NM_002744.6

p.K391R

c.1172A>G

1 paper

NM_002744.6

p.V382I

c.1144G>A

1 paper

NM_002744.6

p.G371R

c.1111G>A

1 paper

NM_002744.6

p.G371R

c.1111G>C