Varaico: Literature-Extracted Genetic Variants

PRKCZ

104 papers

RefSeq Summary

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike...

Pfam Domains

PB1aa 15–98UCSCPB1 domain

C1_1aa 131–183UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 252–518UCSCProtein kinase domain

Pkinase_Caa 539–580UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C zeta

HGNC Alias Symbol

PKC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002744.6

p.M441V

c.1321A>G

Surrounding Variants

1 paper

NM_002744.6

p.D456V

c.1367A>T

1 paper

NM_002744.6

p.V469Splc

c.1405+1G>A

1 paper

NM_002744.6

p.K495_D496Splc

c.1485+166G>A

1 paper

NM_002744.6

p.K495_D496Splc

c.1486-67A>G

2 papers

NM_002744.6

p.S514F

c.1541C>T

1 paper

NM_002744.6

p.F517V

c.1549T>G

1 paper

NM_002744.6

p.D522G

c.1565A>G

1 paper

NM_002744.6

p.L525_L526Splc

c.1575+32A>C

1 paper

NM_002744.6

p.G429Splc

c.1285+55G>C

1 paper

NM_002744.6

p.E426K

c.1276G>A

2 papers

NM_002744.6

p.G425R

c.1273G>A

2 papers

NM_002744.6

p.G425R

c.1273G>C