Varaico: Literature-Extracted Genetic Variants

PRKD2

90 papers

RefSeq Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecys...

Pfam Domains

Ubiquitin_PRKD1_Naa 44–127UCSCSerine/threonine-protein kinase D1-like, ubiquitin-like domain

C1_1aa 139–191UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 265–317UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PHaa 398–478UCSCPH domain

Pkinaseaa 553–807UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase D2

HGNC Alias Symbols

HSPC187; DKFZP586E0820

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_016457.5

p.E873K

c.2617G>A

Surrounding Variants

1 paper

NM_016457.5

p.G848E

c.2543G>A

1 paper

NM_016457.5

p.A835V

c.2504C>T

1 paper

NM_016457.5

p.T812M

c.2435C>T

1 paper

NM_016457.5

p.L807S

c.2420T>C

1 paper

NM_016457.5

p.F766I

c.2296T>A

1 paper

NM_016457.5

p.A765T

c.2293G>A

1 paper

NM_016457.5

p.A764V

c.2291C>T

2 papers

NM_016457.5

p.Q760R

c.2279A>G

1 paper

NM_016457.5

p.Q760E

c.2278C>G

1 paper

NM_016457.5

p.E753K

c.2257G>A

1 paper

NM_016457.5

p.G738G

c.2214C>T

1 paper

NM_016457.5

p.E721K

c.2161G>A