Varaico: Literature-Extracted Genetic Variants

PRKD2

90 papers

RefSeq Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecys...

Pfam Domains

Ubiquitin_PRKD1_Naa 44–127UCSCSerine/threonine-protein kinase D1-like, ubiquitin-like domain

C1_1aa 139–191UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 265–317UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PHaa 398–478UCSCPH domain

Pkinaseaa 553–807UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase D2

HGNC Alias Symbols

HSPC187; DKFZP586E0820

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_016457.5

p.V680M

c.2038G>A

Surrounding Variants

1 paper

NM_016457.5

p.L681V

c.2041T>G

3 papers

NM_016457.5

p.D695A

c.2084A>C

2 papers

NM_016457.5

p.I701T

c.2102T>C

1 paper

NM_016457.5

p.I701N

c.2102T>A

1 paper

NM_016457.5

p.R708C

c.2122C>T

1 paper

NM_016457.5

p.S710A

c.2128T>G

1 paper

NM_016457.5

p.T714A

c.2140A>G

1 paper

NM_016457.5

p.L718R

c.2153T>G

1 paper

NM_016457.5

p.E721K

c.2161G>A

1 paper

NM_016457.5

p.G738G

c.2214C>T

1 paper

NM_016457.5

p.E753K

c.2257G>A

1 paper

NM_016457.5

p.Q760E

c.2278C>G