Varaico: Literature-Extracted Genetic Variants

PRKD2

90 papers

RefSeq Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecys...

Pfam Domains

Ubiquitin_PRKD1_Naa 44–127UCSCSerine/threonine-protein kinase D1-like, ubiquitin-like domain

C1_1aa 139–191UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 265–317UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PHaa 398–478UCSCPH domain

Pkinaseaa 553–807UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase D2

HGNC Alias Symbols

HSPC187; DKFZP586E0820

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016457.5

p.P231S

c.691C>T

Surrounding Variants

1 paper

NM_016457.5

p.L230Q

c.689T>A

1 paper

NM_016457.5

p.R232C

c.694C>T

1 paper

NM_016457.5

p.S238S

c.714T>A

1 paper

NM_016457.5

p.V263A

c.788T>C

2 papers

NM_016457.5

p.A191V

c.572C>T

1 paper

NM_016457.5

p.C188Y

c.563G>A

1 paper

NM_016457.5

p.S183N

c.548G>A

1 paper

NM_016457.5

p.C172C

c.516C>T

1 paper

NM_016457.5

p.G316W

c.946G>T

1 paper

NM_016457.5

p.E317delFs

c.949delC

2 papers

NM_016457.5

p.V324M

c.970G>A

1 paper

NM_016457.5

p.G348A

c.1043G>C