Varaico: Literature-Extracted Genetic Variants

PRKD2

90 papers

RefSeq Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecys...

Pfam Domains

Ubiquitin_PRKD1_Naa 44–127UCSCSerine/threonine-protein kinase D1-like, ubiquitin-like domain

C1_1aa 139–191UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 265–317UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PHaa 398–478UCSCPH domain

Pkinaseaa 553–807UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase D2

HGNC Alias Symbols

HSPC187; DKFZP586E0820

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016457.5

p.Y87F

c.260A>T

Surrounding Variants

1 paper

NM_016457.5

p.C84F

c.251G>T

1 paper

NM_016457.5

p.D91Y

c.271G>T

1 paper

NM_016457.5

p.E83K

c.247G>A

1 paper

NM_016457.5

p.F81S

c.242T>C

1 paper

NM_016457.5

p.K70insFs

c.210dupG

1 paper

NM_016457.5

p.E56D

c.168G>T

1 paper

NM_016457.5

p.E56D

c.168G>C

1 paper

NM_016457.5

p.H48P

c.143A>C

1 paper

NM_016457.5

p.P39P

c.117G>T

1 paper

NM_016457.5

p.G24fs

c.70_71fs

1 paper

NM_016457.5

p.P23insFs

c.69dupC

1 paper

NM_016457.5

p.G16R

c.46G>C