Varaico: Literature-Extracted Genetic Variants

PRKD3

95 papers

RefSeq Summary

This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulato...

Pfam Domains

Ubiquitin_PRKD1_Naa 59–143UCSCSerine/threonine-protein kinase D1-like, ubiquitin-like domain

C1_1aa 155–206UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 272–324UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PHaa 417–506UCSCPH domain

Pkinaseaa 577–832UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase D3

HGNC Previous Symbol

PRKCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005813.6

p.E845*

c.2533G>T

Surrounding Variants

1 paper

NM_005813.6

p.L839I

c.2515C>A

1 paper

NM_005813.6

p.R851H

c.2552G>A

1 paper

NM_005813.6

p.S857T

c.2570G>C

1 paper

NM_005813.6

p.R861H

c.2582G>A

1 paper

NM_005813.6

p.V872V

c.2616A>C

1 paper

NM_005813.6

p.P874L

c.2621C>T

1 paper

NM_005813.6

p.N882K

c.2646T>G

1 paper

NM_005813.6

p.N882K

c.2646T>A

2 papers

NM_005813.6

p.*891insFs

c.2673dupA

2 papers

NM_005813.6

p.W831*

c.2493G>A

2 papers

NM_005813.6

p.W831*

c.2492G>A

1 paper

NM_005813.6

p.L827F

c.2479C>T