Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 116 variants

8 papers

NM_006259.3

p.N164fs

c.490_491fs

7 papers

NM_006259.3

p.R569*

c.1705C>T

5 papers

NM_006259.3

p.D761fs

c.2281_2282fs

4 papers

NM_006259.3

p.N164insFs

c.491dupA

4 papers

NM_006259.3

p.V470G

c.1409T>G

4 papers

NM_006259.3

p.R678*

c.2032C>T

3 papers

NM_006259.3

p.D761insFs

c.2282dupA

2 papers

NM_006259.3

p.R132Q

c.395G>A

2 papers

NM_006259.3

p.M180I

c.540G>T

2 papers

NM_006259.3

p.M180I

c.540G>C

2 papers

NM_006259.3

p.M180I

c.540G>A

2 papers

NM_006259.3

p.W255*

c.764G>A