Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006259.3

p.D761insFs

c.2282dupA

Surrounding Variants

1 paper

NM_006259.3

p.F762L

c.2284T>C

5 papers

NM_006259.3

p.D761fs

c.2281_2282fs

1 paper

NM_006259.3

p.F762L

c.2286C>G

1 paper

NM_006259.3

p.F762L

c.2286C>A

1 paper

NM_006259.3

p.F741Y

c.2222T>A

1 paper

NM_006259.3

p.Y740*

c.2220C>G

1 paper

NM_006259.3

p.Y740*

c.2220C>A

1 paper

NM_006259.3

p.H738Y

c.2212C>T