Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006259.3

p.P619L

c.1856C>T

Surrounding Variants

1 paper

NM_006259.3

p.D628N

c.1882G>A

1 paper

NM_006259.3

p.D632H

c.1894G>C

1 paper

NM_006259.3

p.G602W

c.1804G>T

2 papers

NM_006259.3

p.K599N

c.1797G>T

2 papers

NM_006259.3

p.K599N

c.1797G>C

1 paper

NM_006259.3

p.F650L

c.1948T>C

1 paper

NM_006259.3

p.F650L

c.1950T>G

1 paper

NM_006259.3

p.F650L

c.1950T>A

1 paper

NM_006259.3

p.Q655*

c.1963C>T

4 papers

NM_006259.3

p.R678*

c.2032C>T

1 paper

NM_006259.3

p.R684Q

c.2051G>A