Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006259.3

p.K591N

c.1773A>T

Surrounding Variants

1 paper

NM_006259.3

p.L590delFs

c.1770delA

1 paper

NM_006259.3

p.D576E

c.1728C>G

1 paper

NM_006259.3

p.D576E

c.1728C>A

1 paper

NM_006259.3

p.D576A

c.1727A>C

1 paper

NM_006259.3

p.D576Y

c.1726G>T

7 papers

NM_006259.3

p.R569*

c.1705C>T

1 paper

NM_006259.3

p.A563T

c.1687G>A

2 papers

NM_006259.3

p.V557I

c.1669G>A

2 papers

NM_006259.3

p.R545Splc

c.1635-1G>C

2 papers

NM_006259.3

p.R545Splc

c.1635-1G>A

2 papers

NM_006259.3

p.R545Splc

c.1634+1G>T

1 paper

NM_006259.3

p.D544Y

c.1630G>T