Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006259.3

p.S500_E501insFs

c.1500_1501insT

Surrounding Variants

1 paper

NM_006259.3

p.L505P

c.1514T>C

1 paper

NM_006259.3

p.K487N

c.1461G>T

1 paper

NM_006259.3

p.K487N

c.1461G>C

4 papers

NM_006259.3

p.V470G

c.1409T>G

1 paper

NM_006259.3

p.Q451H

c.1353G>T

1 paper

NM_006259.3

p.Q451H

c.1353G>C

1 paper

NM_006259.3

p.Q451*

c.1351C>T

1 paper

NM_006259.3

p.A442A

c.1326C>T

1 paper

NM_006259.3

p.M434I

c.1302G>T

1 paper

NM_006259.3

p.M434I

c.1302G>C

1 paper

NM_006259.3

p.M434I

c.1302G>A

1 paper

NM_006259.3

p.R419W

c.1255C>T