Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006259.3

p.W255*

c.765G>A

Surrounding Variants

2 papers

NM_006259.3

p.W255*

c.764G>A

1 paper

NM_006259.3

p.V252insFs

c.755_756insC

1 paper

NM_006259.3

p.N251S

c.752A>G

1 paper

NM_006259.3

p.N239K

c.717T>G

1 paper

NM_006259.3

p.N239N

c.717T>C

1 paper

NM_006259.3

p.W228*

c.684G>A

1 paper

NM_006259.3

p.I225I

c.675C>T

1 paper

NM_006259.3

p.S223S

c.669C>A

1 paper

NM_006259.3

p.K220E

c.658A>G

1 paper

NM_006259.3

p.V284V

c.852A>G

1 paper

NM_006259.3

p.C301S

c.901T>A

1 paper

NM_006259.3

p.C301S

c.902G>C