Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006259.3

p.M180I

c.540G>A

Surrounding Variants

2 papers

NM_006259.3

p.M180I

c.540G>T

2 papers

NM_006259.3

p.M180I

c.540G>C

1 paper

NM_006259.3

p.R187I

c.560G>T

1 paper

NM_006259.3

p.L169P

c.506T>C

4 papers

NM_006259.3

p.N164insFs

c.491dupA

8 papers

NM_006259.3

p.N164fs

c.490_491fs

1 paper

NM_006259.3

p.L163fs

c.487_488fs

1 paper

NM_006259.3

p.K220E

c.658A>G

1 paper

NM_006259.3

p.S223S

c.669C>A

1 paper

NM_006259.3

p.I225I

c.675C>T

1 paper

NM_006259.3

p.W228*

c.684G>A

1 paper

NM_006259.3

p.N239K

c.717T>G