Varaico: Literature-Extracted Genetic Variants

PRKG2

92 papers

RefSeq Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The m...

Pfam Domains

cNMP_bindingaa 186–269UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 304–393UCSCCyclic nucleotide-binding domain

Pkinaseaa 453–711UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cGMP-dependent 2

HGNC Alias Symbols

cGKII; PRKGR2; PKG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006259.3

p.R132Q

c.395G>A

Surrounding Variants

1 paper

NM_006259.3

p.T133N

c.398C>A

1 paper

NM_006259.3

p.E128insFs

c.383_384ins8

1 paper

NM_006259.3

p.N137Y

c.409A>T

1 paper

NM_006259.3

p.S126_A127insFs

c.378_379ins8

1 paper

NM_006259.3

p.V125A

c.374T>C

1 paper

NM_006259.3

p.P140L

c.419C>T

1 paper

NM_006259.3

p.A123A

c.369T>A

1 paper

NM_006259.3

p.G120G

c.360A>T

1 paper

NM_006259.3

p.R150T

c.449G>C

1 paper

NM_006259.3

p.D152Y

c.454G>T

1 paper

NM_006259.3

p.D152E

c.456C>A

1 paper

NM_006259.3

p.V63G

c.188T>G