Varaico: Literature-Extracted Genetic Variants

Gene:PRLR
Variant:p.A597fs

PRLR

176 papers

RefSeq Summary

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dim...

Pfam Domains

EpoR_lig-bindaa 22–120UCSCErythropoietin receptor, ligand binding
EpoR_lig-bindaa 22–120UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

prolactin receptor

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000949.7
p.A597fs
c.1789_1790fs
Surrounding Variants
3 papers
NM_000949.7
p.A597T
c.1789G>A
1 paper
NM_000949.7
p.A591P
c.1771G>C
1 paper
NM_000949.7
p.K590R
c.1769A>G
1 paper
NM_000949.7
p.P581T
c.1741C>A
1 paper
NM_000949.7
p.A615T
c.1843G>A
2 papers
NM_000949.7
p.E578Q
c.1732G>C
1 paper
NM_000949.7
p.A576V
c.1727C>T
1 paper
NM_000949.7
p.H619R
c.1856A>G
1 paper
NM_000949.7
p.N568fs
c.1702_1703fs
1 paper
NM_000949.7
p.L560delFs
c.1680delC
1 paper
NM_000949.7
p.V549G
c.1646T>G
3 papers
NM_000949.7
p.V549M
c.1645G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."