Varaico: Literature-Extracted Genetic Variants

Gene:PRLR
Variant:p.T499A

PRLR

176 papers

RefSeq Summary

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dim...

Pfam Domains

EpoR_lig-bindaa 22–120UCSCErythropoietin receptor, ligand binding
EpoR_lig-bindaa 22–120UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

prolactin receptor

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000949.7
p.T499A
c.1495A>G
Surrounding Variants
1 paper
NM_000949.7
p.P500delins
c.1498_1499delinsTT
1 paper
NM_000949.7
p.P506L
c.1517C>T
3 papers
NM_000949.7
p.N516I
c.1547A>T
1 paper
NM_000949.7
p.E480*
c.1438G>T
1 paper
NM_000949.7
p.E478D
c.1434G>T
1 paper
NM_000949.7
p.E478D
c.1434G>C
1 paper
NM_000949.7
p.R477W
c.1429A>T
1 paper
NM_000949.7
p.Q475R
c.1424A>G
1 paper
NM_000949.7
p.L523S
c.1568T>C
1 paper
NM_000949.7
p.P525S
c.1573C>T
1 paper
NM_000949.7
p.E470D
c.1410G>T
1 paper
NM_000949.7
p.E470D
c.1410G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."