Varaico: Literature-Extracted Genetic Variants

Gene:PRLR
Variant:p.P50P

PRLR

176 papers

RefSeq Summary

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dim...

Pfam Domains

EpoR_lig-bindaa 22–120UCSCErythropoietin receptor, ligand binding
EpoR_lig-bindaa 22–120UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

prolactin receptor

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000949.7
p.P50P
c.150T>A
Surrounding Variants
1 paper
NM_000949.7
p.G51E
c.152G>A
1 paper
NM_000949.7
p.P50S
c.148C>T
1 paper
NM_000949.7
p.W47*
c.140G>A
2 papers
NM_000949.7
p.T45T
c.135C>T
1 paper
NM_000949.7
p.T58N
c.173C>A
2 papers
NM_000949.7
p.T43A
c.127A>G
1 paper
NM_000949.7
p.E42G
c.125A>G
1 paper
NM_000949.7
p.K41K
c.123G>A
1 paper
NM_000949.7
p.K41*
c.121A>T
3 papers
NM_000949.7
p.S61A
c.181T>G
2 papers
NM_000949.7
p.S38S
c.114T>G
1 paper
NM_000949.7
p.S38A
c.112T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."