Varaico: Literature-Extracted Genetic Variants

PSMD3

152 papers

RefSeq Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identic...

Pfam Domains

TPR_PSMD3_Naa 67–364UCSCPSMD3-like, N-terminal TPR repeats

PCIaa 379–462UCSCPCI domain

Rpn3_Caa 465–532UCSCProteasome regulatory subunit C-terminal

Gene Aliases

HGNC Name

proteasome 26S subunit, non-ATPase 3

HGNC Previous Symbol

TSTA2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002809.4

p.V335G

c.1004T>G

Surrounding Variants

1 paper

NM_002809.4

p.L339M

c.1015C>A

1 paper

NM_002809.4

p.G340G

c.1020G>T

1 paper

NM_002809.4

p.D344Y

c.1030G>T

1 paper

NM_002809.4

p.R345W

c.1033C>T

1 paper

NM_002809.4

p.Q350*

c.1048C>T

1 paper

NM_002809.4

p.P351_S352ins4

c.1051_1055ins12

1 paper

NM_002809.4

p.R355G

c.1063C>G

1 paper

NM_002809.4

p.R355C

c.1063C>T

1 paper

NM_002809.4

p.L357F

c.1069C>T

1 paper

NM_002809.4

p.G383V

c.1148G>T

1 paper

NM_002809.4

p.F386L

c.1156T>C

1 paper

NM_002809.4

p.F386L

c.1158T>A