prostaglandin E synthase 3

TEBP

cPGES

prostaglandin E synthase 3 (cytosolic)

Prostaglandin E synthase 3

Cytosolic prostaglandin E2 synthase

Hsp90 co-chaperone

Progesterone receptor complex p23

Telomerase-binding protein p23

This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016].

Varaico: Literature-Extracted Genetic Variants

PTGES3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols