Varaico: Literature-Extracted Genetic Variants

Gene:PTGIR
Variant:p.I293N

PTGIR

83 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macro...

Pfam Domains

7tm_1aa 30–292UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

prostaglandin I2 receptor

HGNC Previous Name

prostaglandin I2 (prostacyclin) receptor (IP)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000960.4
p.I293N
c.878T>A
Surrounding Variants
1 paper
NM_000960.4
p.F295S
c.884T>C
1 paper
NM_000960.4
p.R296H
c.887G>A
1 paper
NM_000960.4
p.K297Q
c.889A>C
1 paper
NM_000960.4
p.P289L
c.866C>T
1 paper
NM_000960.4
p.K297R
c.890A>G
1 paper
NM_000960.4
p.P289A
c.865C>G
1 paper
NM_000960.4
p.A298G
c.893C>G
1 paper
NM_000960.4
p.D288A
c.863A>C
2 papers
NM_000960.4
p.V299A
c.896T>C
1 paper
NM_000960.4
p.P285L
c.854C>T
1 paper
NM_000960.4
p.N284K
c.852C>G
1 paper
NM_000960.4
p.N284K
c.852C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."