Varaico: Literature-Extracted Genetic Variants

Gene:PTGIR
Variant:p.C259Y

PTGIR

83 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macro...

Pfam Domains

7tm_1aa 30–292UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

prostaglandin I2 receptor

HGNC Previous Name

prostaglandin I2 (prostacyclin) receptor (IP)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000960.4
p.C259Y
c.776G>A
Surrounding Variants
1 paper
NM_000960.4
p.C259R
c.775T>C
1 paper
NM_000960.4
p.V264V
c.792C>G
1 paper
NM_000960.4
p.A265A
c.795C>T
1 paper
NM_000960.4
p.D267N
c.799G>A
2 papers
NM_000960.4
p.E271A
c.812A>C
2 papers
NM_000960.4
p.D274A
c.821A>C
5 papers
NM_000960.4
p.R279C
c.835C>T
1 paper
NM_000960.4
p.R279L
c.836G>T
1 paper
NM_000960.4
p.A282T
c.844G>A
1 paper
NM_000960.4
p.N284K
c.852C>G
1 paper
NM_000960.4
p.N284K
c.852C>A
1 paper
NM_000960.4
p.P285L
c.854C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."