Varaico: Literature-Extracted Genetic Variants

Gene:PTGIR
Variant:p.A189_G190delFs

PTGIR

83 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macro...

Pfam Domains

7tm_1aa 30–292UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

prostaglandin I2 receptor

HGNC Previous Name

prostaglandin I2 (prostacyclin) receptor (IP)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000960.4
p.A189_G190delFs
c.565_568del4
Surrounding Variants
1 paper
NM_000960.4
p.L194M
c.580C>A
2 papers
NM_000960.4
p.V196L
c.586G>T
2 papers
NM_000960.4
p.V196L
c.586G>C
1 paper
NM_000960.4
p.S185A
c.553T>G
1 paper
NM_000960.4
p.F184V
c.550T>G
2 papers
NM_000960.4
p.G181A
c.542G>C
1 paper
NM_000960.4
p.N203I
c.608A>T
1 paper
NM_000960.4
p.G204S
c.610G>A
12 papers
NM_000960.4
p.R212C
c.634C>T
1 paper
NM_000960.4
p.R212S
c.634C>A
1 paper
NM_000960.4
p.R212L
c.635G>T
1 paper
NM_000960.4
p.R212P
c.635G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."