Varaico: Literature-Extracted Genetic Variants

Gene:PTGIR
Variant:p.L67P

PTGIR

83 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macro...

Pfam Domains

7tm_1aa 30–292UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

prostaglandin I2 receptor

HGNC Previous Name

prostaglandin I2 (prostacyclin) receptor (IP)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000960.4
p.L67P
c.200T>C
Surrounding Variants
1 paper
NM_000960.4
p.V71L
c.211G>T
1 paper
NM_000960.4
p.V71L
c.211G>C
1 paper
NM_000960.4
p.V71M
c.211G>A
1 paper
NM_000960.4
p.L62M
c.184C>A
2 papers
NM_000960.4
p.D60A
c.179A>C
1 paper
NM_000960.4
p.T59I
c.176C>T
2 papers
NM_000960.4
p.Y75F
c.224A>T
1 paper
NM_000960.4
p.Y75S
c.224A>C
3 papers
NM_000960.4
p.R77C
c.229C>T
1 paper
NM_000960.4
p.A57E
c.170C>A
1 paper
NM_000960.4
p.N78I
c.233A>T
1 paper
NM_000960.4
p.T54S
c.160A>T
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