Varaico: Literature-Extracted Genetic Variants

Gene:PTGR1
Variant:p.K328I

PTGR1

35 papers

RefSeq Summary

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 ...

Pfam Domains

ADH_N_2aa 5–105UCSCN-terminal domain of oxidoreductase
ADH_zinc_Naa 153–293UCSCZinc-binding dehydrogenase

Gene Aliases

HGNC Name

prostaglandin reductase 1

HGNC Previous Symbol

LTB4DH

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001146108.2
p.K328I
c.983A>T
Surrounding Variants
1 paper
NM_001146108.2
p.P256S
c.766C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."