Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.E539D

c.1617A>C

Surrounding Variants

1 paper

NM_000963.4

p.E539D

c.1617A>T

1 paper

NM_000963.4

p.G541A

c.1622G>C

1 paper

NM_000963.4

p.G538R

c.1612G>A

1 paper

NM_000963.4

p.S534R

c.1602C>A

3 papers

NM_000963.4

p.Q551R

c.1652A>G

1 paper

NM_000963.4

p.S552C

c.1655C>G

1 paper

NM_000963.4

p.L553delFs

c.1658delA

1 paper

NM_000963.4

p.N523K

c.1569T>G

1 paper

NM_000963.4

p.N523K

c.1569T>A

1 paper

NM_000963.4

p.N556S

c.1667A>G

2 papers

NM_000963.4

p.G522S

c.1564G>A

2 papers

NM_000963.4

p.L520F

c.1558C>T