Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.R442K

c.1325G>A

Surrounding Variants

1 paper

NM_000963.4

p.R442S

c.1326G>T

1 paper

NM_000963.4

p.R442S

c.1326G>C

2 papers

NM_000963.4

p.Q443Q

c.1329G>A

1 paper

NM_000963.4

p.M444I

c.1332G>T

1 paper

NM_000963.4

p.M444I

c.1332G>C

1 paper

NM_000963.4

p.M444I

c.1332G>A

1 paper

NM_000963.4

p.V430_K432del3

c.1288_1295del9

1 paper

NM_000963.4

p.E451K

c.1351G>A

1 paper

NM_000963.4

p.V433I

c.1297G>A

1 paper

NM_000963.4

p.K432R

c.1295A>G

1 paper

NM_000963.4

p.Q431H

c.1293G>C

1 paper

NM_000963.4

p.R453H

c.1358G>A