Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.K432R

c.1295A>G

Surrounding Variants

1 paper

NM_000963.4

p.Q431H

c.1293G>C

1 paper

NM_000963.4

p.V433I

c.1297G>A

1 paper

NM_000963.4

p.P427_V430del0

c.1279_1290del12

1 paper

NM_000963.4

p.Q431*

c.1291C>T

1 paper

NM_000963.4

p.V430_K432del3

c.1288_1295del9

25 papers

NM_000963.4

p.V430V

c.1290A>G

1 paper

NM_000963.4

p.A429T

c.1285G>A

1 paper

NM_000963.4

p.P428A

c.1282C>G

1 paper

NM_000963.4

p.R424S

c.1272G>T

1 paper

NM_000963.4

p.R424S

c.1272G>C

1 paper

NM_000963.4

p.G423V

c.1268G>T

4 papers

NM_000963.4

p.G422D

c.1265G>A